![]() Under stressful conditions, the mother cell can form highly resistant endospores which can lie dormant for many years and germinating when environmental conditions are favourable. On the contrary, disinfectants with sporicidal activity includes those containing peracetic acid, hydrogen peroxide, and chlorine compounds. Bacterial spores are resistant towards disinfectants containing only chlorhexidine, quaternary ammonium compounds, and phenolic compounds. These endospores remain dormant until the environment is favorable to grow. ![]() Some examples of spore-forming bacteria include Bacillus cereus, Bacill us subtilis, and Clostridium tetani. “The toughest player in the game.” - Spore-forming bacteria are known to be the toughest microorganism due to their ability to form a spore coat known as an endospore when under stress to protect themselves from dying. Firstly, how does the resistance of these microorganisms rank? The diagram below shows an overview of the antimicrobial spectrum of disinfectants from the most resistant to least resistant microorganism. Today, we would like to provide an insight into the structure of these microorganisms and how that contributes to their resistance towards disinfectants. Perhaps unsurprisingly, this is due to the cellular structure of the microorganism. We mentioned that the efficacy of these substances against different microorganisms and how some microorganisms show resistance towards some compounds. ![]() A few weeks ago, we published a blog about the active substances commonly found in disinfectants and antiseptics.
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